B-Vitamins

B-Vitamins

B-vitamins

The B-vitamins are eight water-soluble vitamins that work together as co-enzymes to support multiple aspects of cellular function.* Several of the B-vitamins are intricately involved in the catabolic process of generating energy within cells, and inadequate intake in some or all of the B-vitamins may have a negative impact on energy generation.1*

B-vitamins include:

  • B1 (thiamin)
  • B2 (riboflavin)
  • B3 (niacin)
  • B5 (pantothenic acid)
  • B6 (pyridoxine)
  • B7 (biotin)
  • B9 (folate)
  • B12 (cobalamin)

Properties and mechanism of action

Thiamine, riboflavin, niacin, and pantothenic acid play a direct role in the formation of adenosine triphosphate (ATP), which captures chemical energy obtained from the breakdown of food molecules and releases it to fuel other cellular processes.1*

Vitamin B6 is involved in more than 100 enzyme reactions, mostly related to protein metabolism.* Vitamin B6 also supports cognitive development, and is involved in gluconeogenesis and glycogenolysis, immune function, and the formation of hemoglobin.2*

Biotin acts as a coenzyme for multiple carboxylases, which are important for metabolic processes.* Recently, biotin has been found to play a role in cell signaling and epigenetic regulation.3*

Folate coenzymes take part in a variety of reactions critical to the metabolism of nucleic acids and amino acids, and play an important role in regulating normal cell division.4*

Vitamin B12 is required for the development and function of the central nervous system, the formation of healthy red blood cells, and the synthesis of DNA.5*

Scientific support

Several studies have shown that supplementation with multivitamins containing a vitamin B complex may have significant benefits for brain function.1,6*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient details are provided as general information and are not intended to be associated with any specific Zarbee’s® products.

REFERENCES: 1. Kennedy DO. B Vitamins and the brain: mechanisms, dose and efficacy–a review. Nutrients. 2016;8(2):68. 2. National Institutes of Health. Vitamin B6 fact sheet for health professionals. June 2, 2022. Accessed August 22, 2022. https://ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/ 3. Bistas KG, Tadi P. Biotin. July 4, 2022. Accessed August 22, 2022. https://www.ncbi.nlm.nih.gov/books/NBK554493/ 4. National Institutes of Health. Folate fact sheet for health professionals. March 29, 2021. Accessed August 22, 2022. https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/ 5. National Institutes of Health. Vitamin B12 fact sheet for health professionals. March 9, 2022. Accessed August 22, 2022. https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/ 6. Kennedy DO, Veasey R, Watson A, et al. Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males. Psychopharmacology (Berl). 2010;211(1):55-68.